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Obesity

Understanding the Effect of CagriSema, Cagrilintide, and Semaglutide on Muscle Health (Role of Amylin Signature in Muscle Health)

Locations

Denmark

Start date

10/04/2026

Identifiers

Trial ID NN9838-8411,
NCT number NCT07527195,
Eudract number Not Available

Summary

The purpose of this clinical study is to look into how study medicines CagriSema (cagrilintide and semaglutide), cagrilintide, and semaglutide affects muscle health in people with excess body weight and slightly higher than normal blood sugar as they lose weight. Participants will either get CagriSema (a new study drug), cagrilintide (a new study drug), semaglutide (a drug that doctors can already prescribe to treat people with type 2 diabetes and excess body weight) or placebo (a placebo looks like the treatment being tested but doesn't have any active ingredients in it). Which treatment participants will get is decided by chance. Participants will be in this clinical study up to 15 months.

Trial Overview:

Condition

Obesity

Treatment

DRUG: Cagrilintide

DRUG: Semaglutide

DRUG: Placebo cagrilintide

DRUG: Placebo semaglutide

Study type

INTERVENTIONAL

Trial duration

Apr 10 2026 - Jun 09 2028

Participants

100

Phase

I

Are you eligible?

true

Gender

Male and female
true

Age

50 to 70 years old

Find out how you can participate

Questions or concerns

Do you have any question about what it’s like being a clinical volunteer? Have a look at our answers to frequently asked questions.

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