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Obesity

A Research Study to Look Into the Long-term Effect on Weight Loss of CagriSema in People With Obesity

Locations

Belgium, Canada, Denmark, Portugal, United Kingdom, United States

Start date

10/02/2025

Identifiers

Trial ID NN9838-7859,
NCT number NCT06780449,
Eudract number Not Available

Summary

This study will look at how well CagriSema helps people with obesity lose weight compared to a "dummy medicine". CagriSema is a new medicine developed by Novo Nordisk. CagriSema cannot yet be prescribed by doctors. The study has two parts: First part is called the main phase and will last for 2 years, and second part is called the extension phase and will last for 1 year. In the main phase participants will either get CagriSema or "dummy medicine". Which treatment participants get is decided by chance and is not known by participants or the study doctor. In the extension phase participants will get either CagriSema or slowly reduce participants dose of CagriSema if participants had CagriSema in the main phase. Which treatment participants get is decided by chance and is not known by participants or the study doctor in both phases. If participants had "dummy medicine" in the main phase, participants will get CagriSema in the extension phase. Like all medicines, the study medicine may have side effects.

Trial Overview:

Condition

Obesity

Treatment

DRUG: Cagrilintide

DRUG: Semaglutide

DRUG: Placebo cagrilintide

DRUG: Placebo semaglutide

Study type

INTERVENTIONAL

Trial duration

Feb 10 2025 - Nov 17 2028

Participants

400

Phase

III

Are you eligible?

Gender

Male and female

Age

18 years and older

Questions or concerns

Do you have any question about what it’s like being a clinical volunteer? Have a look at our answers to frequently asked questions.

This site contains information about clinical trials sponsored by Novo Nordisk. It is not intended to replace the advice of a healthcare professional and should not be construed as providing advice or making a recommendation. The information on this site should not be relied on as the basis for any decision or action. Only a physician can determine whether a specific product is correct for a particular patient. If you have questions regarding any information contained on this site you should consult a physician.