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Diabetes Obesity Other

A Research Study to See if Kidney Damage in People With Chronic Kidney Disease and Type 2 Diabetes Living With Overweight or Obesity Can be Reduced by CagriSema Compared to Semaglutide, Cagrilintide and Placebo

Locations

Argentina, Brazil, Canada, France, Greece, Hungary, India, Japan, Poland, Slovakia, Spain, Thailand, United States

Start date

01/04/2024

Identifiers

Trial ID NN9388-7700,
NCT number NCT06131372,
Eudract number 2023-505857-42

Summary

This study will look if CagriSema can lower kidney damage in people with chronic kidney disease (CKD), type 2 diabetes (T2D) and overweight or obesity. CagriSema is a new investigational medicine. CagriSema cannot yet be prescribed by doctors. The study will compare CagriSema to the 2 medicines semaglutide and cagrilintide, when they are taken alone. It will also compare CagriSema to a "dummy" medicine (also called placebo) without any active ingredient. Participant will either get CagriSema, semaglutide, cagrilintide or placebo. Which treatment participant will get is decided by chance (like flipping a coin). Study doctor will not know which of the study medicines participant will get. For each participant, the study will last for about 35 weeks.

Trial Overview:

Condition

Chronic Kidney Disease

Type 2 Diabetes

Obesity

Treatment

DRUG: Cagrilintide

DRUG: Semaglutide

DRUG: Placebo

Study type

INTERVENTIONAL

Trial duration

Apr 01 2024 - Dec 01 2025

Participants

618

Phase

II

Are you eligible?

Gender

Male and female

Age

18 years and older

Questions or concerns

Do you have any question about what it’s like being a clinical volunteer? Have a look at our answers to frequently asked questions.

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