Condition
Heart Failure
Locations
Argentina, Australia, Austria, Belgium, Bosnia and Herzegovina, Brazil,
Bulgaria, Canada, China, Colombia, Croatia, Czechia, Denmark, Estonia,
Finland, France, Germany, Greece, Hungary, India, Ireland, Israel,
Italy, Japan, Korea, Republic of, Latvia, Lithuania, Malaysia, Mexico,
Netherlands, North Macedonia, Norway, Poland, Portugal, Romania, Serbia,
Singapore, Slovakia, Slovenia, South Africa, Spain, Taiwan, Thailand,
Turkey, United Kingdom, United States
Start date
08/05/2023
Identifiers
Trial ID
EX6018-4915,
NCT number NCT05636176,
Eudract number Not Available
NCT number NCT05636176,
Eudract number Not Available
Summary
This study will be done to see if ziltivekimab can be used to treat people living with heart failure and inflammation. Participants will either get ziltivekimab or placebo. Participants will get study medicine for once-monthly injections either in a pre-filled syringe to inject the study medicine into a skinfold or a pen-injector to inject the study medicine into flat skin. The study is expected to last for up to 4 years. Participants will have up to 20 clinic visits. Participants will have to use a study app on their phone to record and share information about all their injections of study medicine and to fill in questionnaires.
Trial Overview:
Treatment
DRUG: Ziltivekimab
DRUG: Placebo
Study type
INTERVENTIONAL
Trial duration
May 08 2023 - Jul 02 2027
Participants
5600
Phase
III
Are you eligible?
Gender
Male and female
Age
18 years and older
Find out how you can participate
Questions or concerns
Do you have any question about what it’s like being a clinical volunteer? Have a look at our answers to frequently asked questions.
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